Progesteron

Progesteron, part of the hormone class of the Gestagene, is a female sex hormone, that from the corpus luteum in the second phase of the Menstruationszyklus and, in substantially higher quantities, while of the Plazenta one forms for the pregnancy. Small Progesteronmengen becomes with women and men alsofrom the suprarenal body crust synthesizes.

Technically it from Stigmasterin (in soy beans - oil contain) is synthesized.

structure

Progesteron is as Steroidhormon a derivative of the Cholesterins, from which it is synthesized also in the human organism; it has the sum formula C ₂₁ H ₃₀O ₂.

physiology

Progesteron is synthesized and paid particularly in the corpus luteum by the Granulosazellen and in the Plazenta, in smaller quantities also by other fabrics.
The payment of the hormone is stimulated by LH. The release causes one for those Nidation necessary modification of the Endometriums proliferated, particularly the Lamina functionalis in the gland-rich and strongly supplied with blood Decidua as well as an adjustment of the Uterusmuskulatur at the increasing embryos.

In some steroidproduzierenden cells of the gonad functions the Progesteron as basic material for the synthesis of androgens (maleSex hormones) and Östrogenen (female sex hormones).

Progesteron is metabolisiert to Pregnandiol and eliminated after Glucuronidierung over the urine.

result

pathophysiology increased Progesteronwerte apart from the pregnancy particularly in the case of ovary tumors and in the case of the adrenogentitalen syndrome (AGS). With cycle disturbances and with the so-called. Hypogonadismus, oneUnderdevelopment of the ovaries, is degraded the Progesteronkonzentration.

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