Pepsin
Pepsin (EC.3.4.23.1-3) Animal stomach proteolytic enzyme. One of aspartic acid protease.
Table of contents |
Character
GeneTranslationThe product inactive type is the precusorThe Pepsi-Cola no geneIt is made with mucous membrane of the stomach as. This hydrochloric acidpH, becomes the pepsin of active type by cutting down the professional arrangement of N terminal side with processing of two stages. Strongly it is aciditypH2.Vicinity of 0 is optimum condition. One time when it makes neuter alkaline condition, three-dimensional structure denaturalizes the pepsin which is activated irreversibly and loses activity.
Substrate peculiarity
The acidic amino acid residue of the protein peptide chain - C terminal side of the arrangement which continues with the aromatic amino acid residue is cut off.
Inhibitor
It is obstructed by pepstatin A and the like.
Related item
- digestion
- digestion enzyme
- protease
